SpecificityThe mouse monoclonal antibody NK92.39 recognizes an extracellular epitope of CD96, a transmembrane glycoprotein expressed at low levels on resting, and at high levels on activated T and NK cells, as well as on many T cell leukemias.
ApplicationFC (QC tested)
Application detailsFlow cytometry: Recommended dilution: 1-12 µg/ml
Immunogenhuman NK92 cell line
Other namesTACTILE, MGC22596
PreparationPurified by protein-A affinity chromatography
FormulationPhosphate buffered saline (PBS) solution with 15 mM sodium azide
Storage and handlingStore at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.
Exbio licence noteThe product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden.Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
Product specific references:
Eriksson EM, Keh CE, Deeks SG, Martin JN, Hecht FM, Nixon DF: Differential expression of CD96 surface molecule represents CD8⁺ T cells with dissimilar effector function during HIV-1 infection. PLoS One. 2012;7(12):e51696.PubMed
Fuchs A, Cella M, Giurisato E, Shaw AS, Colonna M: Cutting edge: CD96 (tactile) promotes NK cell-target cell adhesion by interacting with the poliovirus receptor (CD155). J Immunol. 2004 Apr 1;172(7):3994-8.PubMed