EXBIO/Anti-Ms LPAM-1 Purified Azide Free/0.1 mg/10-747-C100,EXBIO,,EXBIO,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：EXBIO/Anti-Ms LPAM-1 Purified Azide Free/0.1 mg/10-747-C100

产品编号：10-747-C100

市场价：¥0.00

场地：美国(厂家直采)

产品分类：蛋白类>多肽>多肽合成>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：待定

品牌： EXBIO

公司：EXBIO

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商品介绍

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References

Isotype

Rat IgG2a kappa

Specificity

The rat monoclonal antibody DATK32 recognizesan extracellular epitope of integrin alpha 4 (CD49d) and integrin beta7 (Ly69) components of mouse LPAM-1 complex, which is expressed on the majority of peripheral lymphocytes, as well as on subsets of thymocytes and bone marrow cells.

Application

IP, FC (QC tested), IHC(F), FUNC

Reactivity

Mouse

Immunogen

TK1 cells

Other names

Integrin alpha 4 beta 7, CD49d / Ly69

Concentration

1 mg/ml

Preparation

Purified by protein-A affinity chromatography

Formulation

Phosphate buffered saline (PBS) solution with 15 mM sodium azide

Storage and handling

Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.

The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden.Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.

Flow cytometry surface staining pattern of murine splenocyte suspension stained using anti-mouse LPAM-1 (DATK32) purified antibody (concentration in sample 2 μg/ml) DAR APC.

Separation of murine LPAM-1 positive cells (red-filled) from LPAM-1 negative cells (black-dashed) in flow cytometry analysis (surface staining) of murine splenocyte suspension stained using anti-mouse LPAM-1 (DATK32) purified antibody (concentration in sample 2 μg/ml) DAR APC.

General references:

Reese SR, Kudsk KA, Genton L, Ikeda S: l-selectin and alpha4beta7 integrin, but not ICAM-1, regulate lymphocyte distribution in gut-associated lymphoid tissue of mice. Surgery. 2005 Feb;137(2):209-15. PubMed

Yang Y, Cardarelli PM, Lehnert K, Rowland S, Krissansen GW: LPAM-1 (integrin alpha 4 beta 7)-ligand binding: overlapping binding sites recognizing VCAM-1, MAdCAM-1 and CS-1 are blocked by fibrinogen, a fibronectin-like polymer and RGD-like cyclic peptides. Eur J Immunol. 1998 Mar;28(3):995-1004. PubMed

Altevogt P, Hubbe M, Ruppert M, Lohr J, von Hoegen P, Sammar M, Andrew DP, McEvoy L, Humphries MJ, Butcher EC: The alpha 4 integrin chain is a ligand for alpha 4 beta 7 and alpha 4 beta 1. J Exp Med. 1995 Aug 1;182(2):345-55. PubMed

Product specific references:

Priestley GV, Scott LM, Ulyanova T, Papayannopoulou T: Lack of alpha4 integrin expression in stem cells restricts competitive function and self-renewal activity. Blood. 2006 Apr 1;107(7):2959-67.PubMed

Riedel SS, Mottok A, Brede C, Bäuerlein CA, Jordán Garrote AL, Ritz M, Mattenheimer K, Rosenwald A, Einsele H, Bogen B, Beilhack A: Non-invasive imaging provides spatiotemporal information on disease progression and response to therapy in a murine model of multiple myeloma. PLoS One. 2012;7(12):e52398.PubMed

品牌介绍

EXBIO是研究和临床应用单克隆抗体和试剂的领先制造商，专注于人类细胞标记物的多色流式细胞术分析。

我们拥有超过4000种现成产品的综合产品组合，涵盖血液学，免疫学，癌症，干细胞和细胞生物学等多个领域。凭借经验丰富的细胞计数专家和生物技术工程师，EXBIO为我们的客户提供了广泛选择的荧光色素结合物中经过长期验证的抗体标记。

我们对客户需求的承诺得到我们符合ISO 13485：2016，ISO9001：2015和cGMP（21 CFR part 820）的集成质量管理体系的支持，使我们能够完成我们的使命：

EXBIO努力超越客户最苛刻的期望通过以可承受的价格提供高质量产品和服务的全面组合，从而成为分析细胞仪领域的专家。

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